4-Oxo-4H-chromene-3-carbaldehyde

Names

[ Name ]:
4-Oxo-4H-chromene-3-carbaldehyde

[Synonym ]:
4-Oxo-4H-chromene-3-carbaldehyde
EINECS 241-451-5
3-Formyl-4H-1-benzopyran-4-one
4H-1-Benzopyran-3-carboxaldehyde, 4-oxo-
4-oxochromene-3-carbaldehyde
Chromone-3-aldehyde
3-Formylchromone
4-Oxo-4H-1-benzopyran-3-carboxaldehyde
MFCD00014667

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
303.1±42.0 °C at 760 mmHg

[ Melting Point ]:
151-153 °C(lit.)

[ Molecular Formula ]:
C₁₀H₆O₃

[ Molecular Weight ]:
174.153

[ Flash Point ]:
134.7±27.9 °C

[ Exact Mass ]:
174.031693

[ PSA ]:
47.28000

[ LogP ]:
0.87

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.687

[ Storage condition ]:
Refrigerator (+4°C)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914400090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Formylchromone exhibits salubrious effects against nitrosodiethylamine mediated early hepatocellular carcinogenesis in rats.

Chem. Biol. Interact. 219 , 175-83, (2014)

The salubrious effects of 3-Formylchromone (3-FC) against nitrosodiethylamine (NDEA) mediated early hepatocellular carcinogenesis was investigated in vivo by this study. Male Wistar rats were administ...

3-Formylchromones: potential antiinflammatory agents.

Eur. J. Med. Chem. 45 , 4058-64, (2010)

The synthesis and characterization of 3-formylchromone (1) and its derivatives 2-24 and evaluation of their potential antiinflammatory activities is reported here. These compounds were characterized b...

Synthesis of quinolines from 3-formylchromone.

J. Org. Chem. 73(15) , 6010-3, (2008)

A facile and versatile procedure for the synthesis of 3-(2-hydroxybenzoyl)quinolines and 7H-chromeno[3,2-c]quinolin-7-ones was elaborated on the basis of TMSCl-mediated recyclization of 3-formylchromo...