γ-Cyclodextrin

Names

[ Name ]:
γ-Cyclodextrin

[Synonym ]:
Cyclooctaamylose
MFCD00149574
g-Dextrin
RINGDEX C
(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,38R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56R)-5,10,15,20,25,30,35,40-Octakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.2.2.2.2.2.2.2]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecol (non-preferred name)
gamma-cyclodextrin
(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,38R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56R)-5,10,15,20,25,30,35,40-Octakis(hydroxymethy ;l)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.2.2.2.2.2.2.2]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56- hexadecol
EINECS 241-482-4
Schardinger γ-Dextrin
g-Cyclodextrin
γ-Dextrin
Cyclooctapentylose
γ-Cyclodextrin
Dexy Pearl g-100
Cyclomaltooctaose
Dexy Pearl γ-100
Sugammadex Impurity 17

Biological Activity

[Description]:

γ-Cyclodextrin is an endogenous metabolite.

[Related Catalog]:

Research Areas >> Metabolic Disease

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
845.2°C (rough estimate)

[ Melting Point ]:
267ºC

[ Molecular Formula ]:
C₄₈H₈₀O₄₀

[ Molecular Weight ]:
1297.125

[ Flash Point ]:
450℃

[ Exact Mass ]:
1296.422607

[ PSA ]:
633.20000

[ LogP ]:
-8.97

[ Index of Refraction ]:
1.591

[ Water Solubility ]:
1 M NaOH: 25 mg/mL, may be clear to slightly hazy

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
GU2293080

[ HS Code ]:
3505100000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 3505100000

Articles

Phthalimido-ferrocidiphenol cyclodextrin complexes: Characterization and anticancer activity.

Int. J. Pharm. 491 , 323-34, (2015)

Several ferrocenyl analogues of tamoxifen have already showed strong antiproliferative activity in experimental glioma models. Nevertheless, these compounds are very poorly soluble in water and an ada...

Effect of γ-cyclodextrin on the in vitro skin permeation of a steroidal drug from nanoemulsions: impact of experimental setup.

Int. J. Pharm. 423(2) , 535-42, (2012)

Numerous reports on the enhancement effect of cyclodextrins (CDs) on the skin permeation of dermally applied drugs exist, the majority of which is based on in vitro diffusion cell studies. The specifi...

Development of sucrose stearate-based nanoemulsions and optimisation through γ-cyclodextrin.

Eur. J. Pharm. Biopharm. 79(1) , 58-67, (2011)

Nanoemulsions aimed at dermal drug delivery are usually stabilised by natural lecithins. However, lecithin has a high tendency towards self-aggregation and is prone to chemical degradation. Therefore,...