Methyl cyanoformate
Names
[ CAS No. ]:
17640-15-2
[ Name ]:
Methyl cyanoformate
[Synonym ]:
Methyl cyanoformate
Carbonocyanidic acid, methyl ester
Formic acid, cyano-, methyl ester
Methyl carbonocyanidate
Cyanoformate methyl ester
MFCD00013420
EINECS 241-626-6
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
100.5±0.0 °C at 760 mmHg
[ Melting Point ]:
°Cd ec.)
[ Molecular Formula ]:
C3H3NO2
[ Molecular Weight ]:
85.061
[ Flash Point ]:
26.1±0.0 °C
[ Exact Mass ]:
85.016380
[ PSA ]:
50.09000
[ LogP ]:
-0.26
[ Vapour Pressure ]:
36.6±0.1 mmHg at 25°C
[ Index of Refraction ]:
1.387
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LQ7525000
- CHEMICAL NAME :
- Formic acid, cyano-, methyl ester
- CAS REGISTRY NUMBER :
- 17640-15-2
- BEILSTEIN REFERENCE NO. :
- 1742994
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C3-H3-N-O2
- MOLECULAR WEIGHT :
- 85.07
- WISWESSER LINE NOTATION :
- NCVO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 100 mg/m3/10M
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,920,1986
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 10 mg/m3/6M
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,920,1986
Safety Information
[ Symbol ]:
GHS02, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H300 + H310 + H330-H315-H319
[ Precautionary Statements ]:
P260-P264-P280-P284-P301 + P310-P302 + P350
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T+: Very toxic;
[ Risk Phrases ]:
R10;R26/27/28;R36/37/38
[ Safety Phrases ]:
26-28-36/37-45
[ RIDADR ]:
UN 3275 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
LQ7525000
[ Packaging Group ]:
III
[ Hazard Class ]:
3.2
[ HS Code ]:
2926909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2926909090
[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Med. Chem. 36 , 3503, (1993)
A variety of isosteres of the DNA polymerase inhibitor aphidicolin were synthesized as potential antiherpes agents. Modeling studies indicated that the bicyclooctane C, D rings of aphidicolin could be...
Tetrahedron Lett. 34 , 8553, (1993)
Tetrahedron 48 , 7979, (1992)