FT-001
Names
[ CAS No. ]:
1778655-51-8
[ Name ]:
FT-001
Biological Activity
[Description]:
FT-001 is a novel potent, orally acitve inhibitor of BET bromodomain with IC50 of 0.1 uM for BRD4 BD1; inhibits the expression of MYC in the MV-4-11 cell line with IC50 of 0.46 uM, shows anti-proliferative activity with IC50 of 0.22 uM; displays complete tumor growth inhibition in mouse MV-4-11 xenograft model.
[References]
References 1. Millan DS, et al. ACS Med Chem Lett. 2017 Jul 14;8(8):847-852. View Related Products by Target Bromodomain
Chemical & Physical Properties
[ Molecular Formula ]:
C25H29N3O4S
[ Molecular Weight ]:
467.584