Phenylphosphinic acid

Names

[ Name ]:
Phenylphosphinic acid

[Synonym ]:
Phosphonousacid,phenyl
phenyl-phosphinicaci
Phosphinicacid,phenyl
Phosphinic acid, P-phenyl-
Hydroxyphenylphosphine oxide
MFCD00002131
Phosphinic acid, phenyl-
Phenylphosphinic acid
phenyl-H-phosphinic acid
phenyl phosphinic acid
PHENYLPHOSPHONOUS ACID
phenylphospho acid
Benzenephosphonous Acid
Coproporphyrin I-15N4
EINECS 217-217-3
Benzenephosphinic acid

Chemical & Physical Properties

[ Boiling Point ]:
285.1±23.0 °C at 760 mmHg

[ Melting Point ]:
83-85 °C(lit.)

[ Molecular Formula ]:
C₆H₇O₂P

[ Molecular Weight ]:
142.092

[ Flash Point ]:
126.2±22.6 °C

[ Exact Mass ]:
142.018372

[ PSA ]:
60.77000

[ LogP ]:
-0.59

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Water Solubility ]:
7.7 g/100 mL (25 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SZ5462500

CHEMICAL NAME :: Phosphinic acid, phenyl-

CAS REGISTRY NUMBER :: 1779-48-2

BEILSTEIN REFERENCE NO. :: 2802244

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C6-H7-O2-P

MOLECULAR WEIGHT :: 142.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555311 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1345 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555311

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >625 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 2,56,1950

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >4640 mg/kg

TOXIC EFFECTS :: Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555311

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;Xn:Harmful;

[ Risk Phrases ]:
R22;R34;R37/38;R41

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
SZ5462500

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

1H-17O nuclear quadrupole double resonance in phenylphosphinic acid and phenylphosphonic acid. 17O quadrupole coupling in P = O and P-O-H bonds.

Magn. Reson. Chem. 46(10) , 969-73, (2008)

The (17)O nuclear quadrupole resonance (NQR) frequencies have been measured in phenylphosphinic acid and phenylphosphonic acid using nuclear quadrupole double resonance. The quadrupole coupling consta...

First principles NMR calculations of phenylphosphinic acid C6H5HPO(OH): assignments, orientation of tensors by local field experiments and effect of molecular motion.

J. Magn. Reson. 187(1) , 131-40, (2007)

The complete set of NMR parameters for (17)O enriched phenylphosphinic acid C(6)H(5)HP( *)O(*OH) is calculated from first principles by using the Gauge Including Projected Augmented Wave (GIPAW) appro...

Photophysical and structural impact of phosphorylated anions associated to lanthanide complexes in water.

Inorg. Chem. 44(20) , 7151-60, (2005)

A new ligand, LC, bis-[(6'-carboxy-2,2'-bipyridine-6-yl)]phenylphosphine oxide, in which the tridentate 6-carboxy-2,2'-bipyridyl arms are directly linked to a phenylphosphine oxide fragment, has been ...