5-Bromo-2-fluorobenzonitrile
Names
[ CAS No. ]:
179897-89-3
[ Name ]:
5-Bromo-2-fluorobenzonitrile
[Synonym ]:
2-Fluoro-5-bromobenzonitrile
3-bromo-6-fluorobenzonitrile
MFCD00143424
3-cyano-4-fluoro-bromobenzene
5-Bromo-2-fluorobenzonitrile
3-bromo-6-fluorobenzenecarbonitrile
5-bromo-2-fluoro-benzonitrile
Benzonitrile, 5-bromo-2-fluoro-
NCR BF EE
Benzonitrile,5-broMo-2-fluoro
3-cyano-4-flurobromobenzene
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
220.4±20.0 °C at 760 mmHg
[ Melting Point ]:
76-81 °C
[ Molecular Formula ]:
C7H3BrFN
[ Molecular Weight ]:
200.008
[ Flash Point ]:
87.1±21.8 °C
[ Exact Mass ]:
198.943283
[ PSA ]:
23.79000
[ LogP ]:
1.92
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.578
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S36/37/39-S26-S22-S36
[ RIDADR ]:
3439
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2926909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2926909090
[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Bioorg. Med. Chem. 14(20) , 6832-46, (2006)
A series of heteroaryl-pyridine containing inhibitors of Akt are reported. The synthesis and structure-activity relationships are discussed, leading to the discovery of a indazole-pyridine analogue (K...
Synthesis of structurally identical fluorine-18 and iodine isotope labeling compounds for comparative imaging.Bioconjug. Chem. 14(2) , 287-94, (2003)
The synthesis of a benzophenone-based labeling compound designed for comparative imaging studies with both in vivo positron emission tomograph (PET) and single-photon computed tomography (SPECT) and e...
Microwave-assisted synthesis of 3-aminobenzo [b] thiophene scaffolds for the preparation of kinase inhibitors. Bagley MC, et al.Org. Biomol. Chem. , (2015)