INDINAVIR (100 MG)F0D3080.971MG/MG(AI)
Names
[ CAS No. ]:
180683-37-8
[ Name ]:
INDINAVIR (100 MG)F0D3080.971MG/MG(AI)
[Synonym ]:
(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide,hydrate
Chemical & Physical Properties
[ Boiling Point ]:
877.9ºC at 760 mmHg
[ Melting Point ]:
158 °C
[ Molecular Formula ]:
C36H49N5O5
[ Molecular Weight ]:
631.80500
[ Flash Point ]:
484.7ºC
[ Exact Mass ]:
631.37300
[ PSA ]:
134.24000
[ LogP ]:
4.35900
[ Vapour Pressure ]:
5.56E-33mmHg at 25°C
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
Articles
Biomaterials 37 , 383-94, (2015)
With the advent of the Highly Active Antiretroviral Therapy, the morbidity and the mortality associated to HIV have been considerably reduced. However, 35-40 million people bear the infection worldwid...
Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of P-glycoprotein substrates in cynomolgus monkeys.J. Pharmacol. Exp. Ther. 350(3) , 578-88, (2014)
The aim of this study was to investigate whether in vivo drug distribution in brain in monkeys can be reconstructed by integrating four factors: protein expression levels of P-glycoprotein (P-gp)/mult...
Drug susceptibility to etravirine and darunavir among Human Immunodeficiency Virus Type 1-derived pseudoviruses in treatment-experienced patients with HIV/AIDS in South Korea.Virol. J. 12(1) , 53, (2015)
In South Korea, about 20 types of antiretroviral drugs are used in the treatment of patients with human immunodeficiency virus/acquired immune deficiency syndrome. Since 2010, raltegravir, etravirine,...