3-Aminopyrazole

Names

[ Name ]:
3-Aminopyrazole

[Synonym ]:
3-Pyrazolamine
5-Pyrazolamine
1H-pyrazol-3-ylamine
EINECS 217-338-1
5-AMINOPYRAZOLE
3-amino-pyrazole
3-AMINOPYROZOLE
1H-Pyrazol-5-amine
3-Amino-pyrazol
3-Aminopyarazole
1H-pyrazol-3-amine
MFCD00005236
3-AP

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
334.5±15.0 °C at 760 mmHg

[ Melting Point ]:
34-37 °C(lit.)

[ Molecular Formula ]:
C₃H₅N₃

[ Molecular Weight ]:
83.092

[ Flash Point ]:
182.6±7.6 °C

[ Exact Mass ]:
83.048347

[ PSA ]:
54.70000

[ LogP ]:
-0.29

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.648

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive; Xi:Irritant

[ Risk Phrases ]:
R22;R34;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3263 8/PG 2

[ WGK Germany ]:
3

[ Hazard Class ]:
8.0

[ HS Code ]:
2933199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Trypanotoxic activity of thiosemicarbazone iron chelators.

Exp. Parasitol. 150 , 7-12, (2015)

Only a few drugs are available for treating sleeping sickness and nagana disease; parasitic infections caused by protozoans of the genus Trypanosoma in sub-Saharan Africa. There is an urgent need for ...

Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer.

Cancer Res. 75 , 2863-74, (2015)

Generalized strategies to improve breast cancer treatment remain of interest to develop. In this study, we offer preclinical evidence of an important metabolic mechanism underlying the antitumor activ...

Analysis of gait in rats with olivocerebellar lesions and ability of the nicotinic acetylcholine receptor agonist varenicline to attenuate impairments.

Behav. Brain Res. 291 , 342-50, (2015)

Studies have demonstrated that administration of the neuronal nicotinic receptor agonist varenicline to rats with olivocerebellar lesions attenuates balance deficits on a rotorod and balance beam, but...