1-[(Methylcarbamoyl)oxy]-2,5-pyrrolidinedione

Names

[ Name ]:
1-[(Methylcarbamoyl)oxy]-2,5-pyrrolidinedione

[Synonym ]:
Methyl isocyanate substitute
O-succinimidyl N-methylcarbamate
N-methylcarbamic acid N'-hydroxysuccinimide ester
N-(methylcarbamoyloxy)succinimide
2,5-Pyrrolidinedione, 1-[[(methylamino)carbonyl]oxy]-
N-succinimidyl-N-methyl carbamate
MFCD00800292
MIC substitute
1-[(Methylcarbamoyl)oxy]pyrrolidine-2,5-dione
N-Succinimidyl-N-methylcarbamate
2,5-Dioxopyrrolidin-1-yl methylcarbamate
1-[(Methylcarbamoyl)oxy]-2,5-pyrrolidinedione
N-succinimidyl N-methylcarboxamide

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Melting Point ]:
148-152ºC

[ Molecular Formula ]:
C₆H₈N₂O₄

[ Molecular Weight ]:
172.139

[ Exact Mass ]:
172.048401

[ PSA ]:
75.71000

[ LogP ]:
-1.99

[ Index of Refraction ]:
1.528

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Activated N-nitrosocarbamates for regioselective synthesis of N-nitrosoureas.

J. Med. Chem. 25 , 178, (1982)

A practical and convenient method for synthesizing antitumor compounds, N-alkyl-N-nitrosoureas, regioselectively nitrosated on the nitrogen atom bearing the alkyl group is proposed. N-Alkyl-N-nitrosoc...

K. Takeda et al.

Tetrahedron Lett. 24 , 4569, (1983)