Endosidin-2

Names

[ Name ]:
Endosidin-2

[Synonym ]:
3-Fluoro-N'-[(E)-(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]benzohydrazide
Benzoic acid, 3-fluoro-, 2-[(1E)-(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]hydrazide
Endosidin2
(E)-3-Fluoro-N'-(4-hydroxy-3-iodo-5-methoxybenzylidene)benzohydrazide

Biological Activity

[Description]:

A small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.

[References]

References 1. Zhang C, et al. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E41-50. 2. Drakakaki G, et al. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17850-5. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Molecular Formula ]:
C₁₅H₁₂FIN₂O₃

[ Molecular Weight ]:
414.170

[ Exact Mass ]:
413.987640

[ LogP ]:
2.84

[ Index of Refraction ]:
1.631

Endosidin-2

Names

Biological Activity

Chemical & Physical Properties

Related Compounds