1-(β-D-Xylofuranosyl)-5-methylcytosine

Names

[ CAS No. ]:
18492-10-9

[ Name ]:
1-(β-D-Xylofuranosyl)-5-methylcytosine

Biological Activity

[Description]:

1-(β-D-Xylofuranosyl)-5-methylcytosine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H15N3O5

[ Molecular Weight ]:
257.24

Related Compounds