Y02224

Y02224 is a BET inhibitor. It shows the reasonable antiproliferative effect on leukemia cells.

1. Xue, X. Q.; Zhang, Y.; Liu, Z. X.; Song, M.; Xing, Y. L.; Xiang, Q. P.; Wang, Z.; Tu, Z. C.; Zhou, Y. L.; Ding, K.; Xu, Y. Discovery of benzo[cd]indol-2(1H)-ones as potent and specific BET bromodomain inhibitors: structure-based virtual screening, optimization