DS-1205b free base
Names
[ CAS No. ]:
1855860-24-0
[ Name ]:
DS-1205b free base
Biological Activity
[Description]:
DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.
Chemical & Physical Properties
[ Molecular Formula ]:
C41H42FN5O7
[ Molecular Weight ]:
735.80