1-(4-Nitrophenyl)methanamine hydrochloride (1:1)

Names

[ Name ]:
1-(4-Nitrophenyl)methanamine hydrochloride (1:1)

[Synonym ]:
1-(4-Nitrophenyl)methanamine hydrochloride (1:1)
Benzenemethanamine, 4-nitro-, hydrochloride (1:1)
4-Nitrobenzylamine HCl
p-Nitrobenzylamine hydrochloride
4-NitrobenzylaMine Hydrochloride
Z1R DNW &&HCl
4-nitrobenzylamine hydrochloride salt
(4-nitrophenyl)methanamine Hydrochloride
P-Nitrobenzylamine HCl
MFCD00012863
EINECS 242-441-3

Chemical & Physical Properties

[ Boiling Point ]:
297.5ºC at 760mmHg

[ Melting Point ]:
~265 °C (dec.)(lit.)

[ Molecular Formula ]:
C₇H₉ClN₂O₂

[ Molecular Weight ]:
188.612

[ Flash Point ]:
133.7ºC

[ Exact Mass ]:
188.035248

[ PSA ]:
71.84000

[ LogP ]:
3.07900

[ Vapour Pressure ]:
0.00135mmHg at 25°C

[ Stability ]:
Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DP6705000

CHEMICAL NAME :: Benzylamine, p-nitro-, hydrochloride

CAS REGISTRY NUMBER :: 18600-42-5

LAST UPDATED :: 197901

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H8-N2-O2.Cl-H

MOLECULAR WEIGHT :: 188.63

WISWESSER LINE NOTATION :: Z1R DNW &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#05082

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
DP6705000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2921499090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Graphite powder and multiwalled carbon nanotubes chemically modified with 4-nitrobenzylamine.

ChemPhysChem 6(2) , 352-62, (2005)

We demonstrate that graphite powder and multiwalled carbon nanotubes (MWCNTs) can be derivatised by 4-nitrobenzylamine (4-NBA) simply by stirring the graphite powder or MWCNTs in a solution of acetoni...

Chirality sensing by a fluorescent binaphthocrown ether-polythiophene conjugate.

Chem. Commun. (Camb.) 48(11) , 1641-3, (2012)

Chiral recognition abilities of the title host for (R)- and (S)-α-methyl-4-nitrobenzylamine were examined in the ground and excited states to give a relative affinity (K(R)/K(S)) of 2.16 by spectral t...

The aromatic cage in the active site of monoamine oxidase B: effect on the structural and electronic properties of bound benzylamine and p-nitrobenzylamine.

J. Neural Transm. Gen. Sect. 114(6) , 693-8, (2007)

Computational studies using the ONIOM methods have been performed to probe the catalytic roles of tyrosine residues 398 and 435 which constitute the "aromatic cage" in the active site of MAO-B. The re...