FAUC 1036
Names
[ CAS No. ]:
1869983-83-4
[ Name ]:
FAUC 1036
Biological Activity
[Description]:
A potent, biased allosteric agonist of CXCR3 (pEC50=6.64), selectively induces chemotaxis and receptor internalization, and induces β-arrestin 2 recruitment without any stimulation of G proteins.
[References]
References 1. Milanos L, et al. J Med Chem. 2016 Mar 10;59(5):2222-43. 2. Milanos L, et al. Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15277-15281. View Related Products by Target Chemokine Receptor (CCR and CXCR)
Chemical & Physical Properties
[ Molecular Formula ]:
C45H52N4O6
[ Molecular Weight ]:
744.933