8-Quinolinesulfonyl chloride
Names
[ CAS No. ]:
18704-37-5
[ Name ]:
8-Quinolinesulfonyl chloride
[Synonym ]:
8-quinolinylsulfonyl chloride
MFCD00006808
8-Quinolylsulfonyl chloride
quinolin-8-ylsulfonylchloride
Quinoline-8-sulphonyl chloride
EINECS 242-515-5
8-Chlorosulfonyl-1-benzazine
8-Quinolinesulfonyl chloride
Quinoline-8-sulfonic acid chloride
(8-quinoline)sulfonyl chloride
Quinoline-8-sulfonyl chloride
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
355.9±17.0 °C at 760 mmHg
[ Melting Point ]:
126-129 °C(lit.)
[ Molecular Formula ]:
C9H6ClNO2S
[ Molecular Weight ]:
227.667
[ Flash Point ]:
169.0±20.9 °C
[ Exact Mass ]:
226.980774
[ PSA ]:
55.41000
[ LogP ]:
1.95
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.647
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VC2830000
- CHEMICAL NAME :
- 8-Quinolinesulfonyl chloride
- CAS REGISTRY NUMBER :
- 18704-37-5
- BEILSTEIN REFERENCE NO. :
- 0156347
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C9-H6-Cl-N-O2-S
- MOLECULAR WEIGHT :
- 227.67
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3261 8/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
VC2830000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
29334990
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Bioorg. Med. Chem. 7(11) , 2397-406, (1999)
Reaction of 20 aromatic/heterocyclic sulfonamides containing a free amino, imino, hydrazino or hydroxyl group, with 8-quinoline-sulfonyl chloride afforded a series of water-soluble (as hydrochloride o...
QSAR study on carbonic anhydrase inhibitors: aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties, with topical activity as antiglaucoma agents.Eur. J. Med. Chem. 39(7) , 593-600, (2004)
Quantitative structure-activity-relationship (QSAR) study on aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl carbonic anhydrase (CA) inhibitors has been carried out topologically us...
H. Takaku et al.J. Org. Chem. 45 , 3347, (1980)