Hexachloropropene

Names

[ Name ]:
Hexachloropropene

[Synonym ]:
1,1,2,3,3,3-Hexachloro-1-propene
MFCD00000835
Hexachloropropene
Perchloropropylene
2-chloro-1,1,3,3,3-pentachloropropene
EINECS 217-560-9
RCRA waste no. U243
1,1,2,3,3,3-hexachloroprop-1-ene
PERCHLOROPROPENE
Hexachloropropylene
Hexachlorpropylen
RCRA waste number U243
Propene,hexachloro
1-Propene,1,1,2,3,3,3-hexachloro
Hexachlor-propen
1-Propene, 1,1,2,3,3,3-hexachloro-

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
209.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-73°C

[ Molecular Formula ]:
C₃Cl₆

[ Molecular Weight ]:
248.750

[ Flash Point ]:
69.9±23.3 °C

[ Exact Mass ]:
245.813110

[ LogP ]:
6.08

[ Vapour density ]:
8.3 (vs air)

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.554

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UD0175000

CHEMICAL NAME :: Propene, hexachloro-

CAS REGISTRY NUMBER :: 1888-71-7

BEILSTEIN REFERENCE NO. :: 1766640

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C3-Cl6

MOLECULAR WEIGHT :: 248.73

WISWESSER LINE NOTATION :: GYGUYGXGGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 425 ppm/30M

TOXIC EFFECTS :: Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea Liver - hepatitis (hepatocellular necrosis), diffuse

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 uL/kg

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 ppm/30M

TOXIC EFFECTS :: Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 85 ppm/30M

TOXIC EFFECTS :: Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 15 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,1,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6277 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R23;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3382 6.1/PG 1

[ WGK Germany ]:
3

[ RTECS ]:
UD0175000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2903299090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2903299090

[ Summary ]:
2903299090 other unsaturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Mutagenicity of chloroolefins in the Salmonella/mammalian microsome test. III. Metabolic activation of the allylic chloropropenes allyl chloride, 1,3-dichloropropene, 2,3-dichloro-1-propene, 1,2,3-trichloropropene, 1,1,2,3-tetrachloro-2-propene and hexachloropropene by S9 mix via two different metabolic pathways.

Mutat. Res. 170(1-2) , 1-9, (1986)

In the presence of S9 mix all allylic chloropropenes tested exert considerable indirect mutagenic activity which is most pronounced for 1,2,3-trichloropropene. Lower as well as higher chlorinated deri...