Pactimibe
Names
Biological Activity
[Description]:
[Related Catalog]:
[Target]
ACAT1:4.9 μM (IC50)
ACAT2:3.0 μM (IC50)
ACAT:2 μM (IC50, in the liver)
ACAT:2.7 μM (IC50, in macrophages)
ACAT:4.7 μM (IC50, in THP-1 cells)
oleoyl-CoA:5.6 μM (Ki)
cholesteryl ester formation:6.7 μM (IC50)
[In Vitro]
[In Vivo]
[References]
Chemical & Physical Properties
[ Density]:
1.071
[ Boiling Point ]:
604.4ºC at 760 mmHg
[ Molecular Formula ]:
C25H40N2O3
[ Molecular Weight ]:
416.59700
[ Flash Point ]:
319.3ºC
[ Exact Mass ]:
416.30400
[ PSA ]:
69.64000
[ LogP ]:
5.77610
[ Vapour Pressure ]:
1.86E-15mmHg at 25°C
[ Index of Refraction ]:
1.547