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1,3,4-Oxadiazol-2-amine, 5-phenyl-, monohydrochloride

Names

[ CAS No. ]:
1905-75-5

[ Name ]:
1,3,4-Oxadiazol-2-amine, 5-phenyl-, monohydrochloride

[Synonym ]:
1,3,2,4-Dioxathiazole,5-phenyl-,2-oxide
5-Phenyl-1,3,2,4-Dioxathiazol-2-oxid

Chemical & Physical Properties

[ Density]:
1.276g/cm3

[ Boiling Point ]:
332.3ºC at 760 mmHg

[ Molecular Formula ]:
C8H8ClN3O

[ Molecular Weight ]:
197.62200

[ Flash Point ]:
154.7ºC

[ Exact Mass ]:
197.03600

[ PSA ]:
64.94000

[ LogP ]:
2.70200

[ Vapour Pressure ]:
0.000148mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RO0548600
CHEMICAL NAME :
1,3,4-Oxadiazol-2-amine, 5-phenyl-, monohydrochloride
CAS REGISTRY NUMBER :
1905-75-5
LAST UPDATED :
199203
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C8-H7-N3-O.Cl-H
MOLECULAR WEIGHT :
197.64

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
440 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
>400 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
>60 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961

Related Compounds