ROMK-IN-32
Names
[ CAS No. ]:
1914944-54-9
[ Name ]:
ROMK-IN-32
Biological Activity
[Description]:
ROMK-IN-32 is a potent, selective ROMK inhibitor with IC50 of 17 nM; shows an improved functional hERG/ROMK potency ratio (1176x) and preclinical PK profile; demonstrates blood pressure lowering effects in the spontaneously hypertensive rat model.
[References]
References 1. Dong S, et al. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2559-2566. View Related Products by Target Potassium Channel
Chemical & Physical Properties
[ Molecular Formula ]:
C24H28N4O5
[ Molecular Weight ]:
452.511
Safety Information
[ Hazard Codes ]:
Xi