4-Nitrothalidomide
Names
[ CAS No. ]:
19171-18-7
[ Name ]:
4-Nitrothalidomide
[Synonym ]:
1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-nitro-isoindoline
2-(2,6-dioxo-piperidin-3-yl)-4-nitro-isoindole-1,3-dione
3-(1',3'-Dioxo-4'-nitroisoindolinyl-2')-2,6-dioxopiperidine
2-(2,6-dioxopiperidin-3-yl)-4-nitro-1H-isoindole-1,3(2H)-dione
4-Nitrothalidomide
2-(2,6-dioxopiperidine-3-yl)-4-nitrophthalimide
3-Nitrothalidomide
N-(2,6-Dioxo-3-piperidyl)-3-nitrophthalimide
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-nitro-
2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
Phthalimide,N-(2,6-dioxo-3-piperidyl)-3-nitro
2-(2,6-Dioxo-3-piperidinyl)-4-nitro-1H-isoindole-1,3(2H)-dione
Pomalidomide Impurity 6
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
603.4±50.0 °C at 760 mmHg
[ Molecular Formula ]:
C13H9N3O6
[ Molecular Weight ]:
303.227
[ Flash Point ]:
318.7±30.1 °C
[ Exact Mass ]:
303.049133
[ PSA ]:
132.86000
[ LogP ]:
0.27
[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C
[ Index of Refraction ]:
1.674
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TI4930000
- CHEMICAL NAME :
- Phthalimide, N-(2,6-dioxo-3-piperidyl)-3-nitro-
- CAS REGISTRY NUMBER :
- 19171-18-7
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C13-H9-N2-O6
- MOLECULAR WEIGHT :
- 289.24
- WISWESSER LINE NOTATION :
- T56 BVNVJ FNW C- DT6VMVTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 900 mg/kg
- SEX/DURATION :
- female 7-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 3,987,1964
Safety Information
[ HS Code ]:
2925190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%