1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin
Names
[ CAS No. ]:
19408-74-3
[ Name ]:
1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin
[Synonym ]:
PCDD 70
1,2,3,7,8,9-Hexachlorodibenzodioxin
1,2,3,7,8,9-HxCDD
Dibenzo-p-dioxin,1,2,3,7,8,9-hexachloro
1,2,3,7,8,9-hexachlorinated dibenzodioxin
1,2,3,7,8,9-H6CDD
D 70
1,2,3,7,8,9-hexachlorooxanthrene
1,2,3,6,7,8,9-hexachloro dibenzo-p-dioxin
HxCDD
Chemical & Physical Properties
[ Density]:
1.777g/cm3
[ Boiling Point ]:
478ºC at 760mmHg
[ Molecular Formula ]:
C12H2Cl6O2
[ Molecular Weight ]:
390.86100
[ Flash Point ]:
182.9ºC
[ Exact Mass ]:
387.81900
[ PSA ]:
18.46000
[ LogP ]:
7.50500
[ Vapour Pressure ]:
7.72E-09mmHg at 25°C
[ Index of Refraction ]:
1.666
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HP3310000
- CHEMICAL NAME :
- Dibenzo-p-dioxin, 1,2,3,7,8,9-hexachloro-
- CAS REGISTRY NUMBER :
- 19408-74-3
- BEILSTEIN REFERENCE NO. :
- 1353896
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C12-H2-Cl6-O2
- MOLECULAR WEIGHT :
- 390.84
- WISWESSER LINE NOTATION :
- T C666 BO IOJ DG EG FG LG MG NG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1440 mg/kg
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 60 ug/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - mouse Fibroblast
- DOSE/DURATION :
- 120 pmol/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1485,1987 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 69,33,1997
Safety Information
[ RIDADR ]:
UN 2811
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2932999060
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2932999060
[ Summary ]:
2932999060. Dioxin,Furan(polychorinated dibenzo-p-dioxines,polychlorinated dibenzofurans). VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods). MFN tariff:6.5%. General tariff:20.0%