TGFβRI-IN-1

Names

[ CAS No. ]:
1950628-94-0

[ Name ]:
TGFβRI-IN-1

Biological Activity

[Description]:

TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively[1] .

[Related Catalog]:

Research Areas >> Cancer

[Target]

IC50: 2 nM (TGFβRI)[1].

[References]

[1]. Yong Zhang, et al. Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents. ACS Med. Chem. Lett.20189111117-1122.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₄D₃N₅O₂

[ Molecular Weight ]:
362.40

TGFβRI-IN-1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds