Farglitazar

Names

[ CAS No. ]:
196808-45-4

[ Name ]:
Farglitazar

[Synonym ]:
N-(o-Benzoylphenyl)-O-(2-(5-methyl-2-phenyl-4-oxazolyl)ethyl)-L-tyrosine
L-Tyrosine,N-(2-benzoylphenyl)-o-(2-(5-methyl-2-phenyl-4-oxazolyl)ethyl)
Farglitazar
N-(2-benzoylphenyl)-O-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yI)ethyl]-L-tyrosine
(2S)-((2-benzoylphenyl)amino)-3-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}-propionic acid
2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID

Biological Activity

[Description]:

Farglitazar is a PPARγ agonist that has significant therapeutic benefits such as glycemic control in type 2 diabetic patients.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

Research Areas >> Metabolic Disease

[References]

[1]. Chen L, Yang B, McNulty JA, et al. GI262570, a peroxisome proliferator-activated receptor {gamma} agonist, changes electrolytes and water reabsorption from the distal nephron in rats. J Pharmacol Exp Ther. 2005;312(2):718-725.

Chemical & Physical Properties

[ Boiling Point ]:
793.7ºC at 760 mmHg

[ Molecular Formula ]:
C₃₄H₃₀N₂O₅

[ Molecular Weight ]:
546.61200

[ Flash Point ]:
433.8ºC

[ Exact Mass ]:
546.21500

[ PSA ]:
101.66000

[ LogP ]:
6.68330

[ Vapour Pressure ]:
1.45E-26mmHg at 25°C

[ Index of Refraction ]:
1.639

Farglitazar

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Related Compounds