11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol
Names
[ CAS No. ]:
1977-15-7
[ Name ]:
11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol
[Synonym ]:
5-[3-(Methylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepin-2-ol
5H-Dibenz(b,f)azepin-2-ol,10,11-dihydro-5-(3-(methylamino)propyl)
2-Hydroxydesmethylimipramine
2-hydroxy-desipramine
10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepin-2-ol
Chemical & Physical Properties
[ Density]:
1.117g/cm3
[ Boiling Point ]:
477.9ºC at 760mmHg
[ Melting Point ]:
146-148ºC
[ Molecular Formula ]:
C18H22N2O
[ Molecular Weight ]:
282.38000
[ Flash Point ]:
242.8ºC
[ Exact Mass ]:
282.17300
[ PSA ]:
35.50000
[ LogP ]:
3.69430
[ Vapour Pressure ]:
9.32E-10mmHg at 25°C
[ Index of Refraction ]:
1.596
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HO2990000
- CHEMICAL NAME :
- 5H-Dibenz(b,f)azepin-2-ol, 10,11-dihydro-5-(3-(methylamino)propyl)-
- CAS REGISTRY NUMBER :
- 1977-15-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H22-N2-O
- MOLECULAR WEIGHT :
- 282.42
- WISWESSER LINE NOTATION :
- T C676 BN&T&J B3M1 FQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 31 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 15,187,1966
Safety Information
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%