2H-1-Benzopyran-2-one,4,7-dihydroxy-

Names

[ CAS No. ]:
1983-81-9

[ Name ]:
2H-1-Benzopyran-2-one,4,7-dihydroxy-

[Synonym ]:
4,7-dihydroxy-2H-1-benzopyran-2-one
4,7-Dihydroxycoumarin
Coumarin,4,7-dihydroxy
4,7-dihydroxy-2H-chromen-2-one
4,7-Dihydroxy-cumarin
4,7-Dihydroxy-coumarin
4,7-dihydroxy-chromen-2-one
4,7-Dihydroxy-2-oxo-2H-1-benzopyran
2H-1-BENZOPYRAN-2-ONE,4,7-DIHYDROXY
2,7-dihydroxychromen-4-one

Chemical & Physical Properties

[ Density]:
1.612g/cm3

[ Boiling Point ]:
390ºC at 760mmHg

[ Melting Point ]:
263 °C(dec.)

[ Molecular Formula ]:
C₉H₆O₄

[ Molecular Weight ]:
178.14200

[ Flash Point ]:
166.5ºC

[ Exact Mass ]:
178.02700

[ PSA ]:
70.67000

[ LogP ]:
1.20420

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.711

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites.

Arch. Biochem. Biophys. 564 , 244-53, (2014)

The widely used anticoagulant Coumadin (R/S-warfarin) undergoes oxidation by cytochromes P450 into hydroxywarfarins that subsequently become conjugated for excretion in urine. Hydroxywarfarins may mod...