m-3-g hydrate

Names

[ CAS No. ]:
20290-09-9

[ Name ]:
m-3-g hydrate

[Synonym ]:
(2S,3S,4S,5R,6S)-6-[[(4R,4aR,7S,7aR,12bS)-7-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-9-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.64 g/cm3

[ Boiling Point ]:
745.1ºCat 760 mmHg

[ Melting Point ]:
220-224°C

[ Molecular Formula ]:
C₂₃H₂₇NO₉

[ Molecular Weight ]:
461.46200

[ Flash Point ]:
404.4ºC

[ Exact Mass ]:
461.16900

[ PSA ]:
149.15000

[ Vapour Pressure ]:
2.58E-23mmHg at 25°C

[ Index of Refraction ]:
1.731

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R23/25

[ Safety Phrases ]:
36

[ RIDADR ]:
UN 1230 3/PG 2

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Morphine glucuronidation increases its analgesic effect in guinea pigs.

Life Sci. 109(2) , 104-10, (2014)

Morphine is extensively metabolized to neurotoxic morphine-3-glucuronide (M3G) and opioid agonist morphine-6-glucuronide (M6G). Due to these different roles, interindividual variability and co-adminis...

[Rapid opiate detoxification under anesthesia (RODA)].

Rev. Med. Liege. 68(5-6) , 298-302, (2013)

Rapid Opiate Detoxification under Anesthesia (RODA) involves the use of opiate antagonists combined with anesthesia and pharmacotherapy to reduce withdrawal symptoms. The aim of our study was to measu...

Determination of opiates in whole blood and vitreous humor: a study of the matrix effect and an experimental design to optimize conditions for the enzymatic hydrolysis of glucuronides.

J. Anal. Toxicol. 36(3) , 162-70, (2012)

Undoubtedly, whole blood and vitreous humor have been biological samples of great importance in forensic toxicology. The determination of opiates and their metabolites has been essential for better in...