6-METHOXY-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE

Names

[ CAS No. ]:
20315-68-8

[ Name ]:
6-METHOXY-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE

[Synonym ]:
MFCD00012071
6-methoxytryptoline
6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
6-MeOthbc

Chemical & Physical Properties

[ Density]:
1.198 g/cm3

[ Boiling Point ]:
388.6ºC at 760 mmHg

[ Melting Point ]:
219-222ºC(lit.)

[ Molecular Formula ]:
C₁₂H₁₄N₂O

[ Molecular Weight ]:
202.25200

[ Flash Point ]:
188.8ºC

[ Exact Mass ]:
202.11100

[ PSA ]:
37.05000

[ LogP ]:
2.15100

[ Vapour Pressure ]:
3.03E-06mmHg at 25°C

[ Index of Refraction ]:
1.639

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV0725000

CHEMICAL NAME :: 1H-Pyrido(3,4-b)indole, 2,3,4,9-tetrahydro-6-methoxy-

CAS REGISTRY NUMBER :: 20315-68-8

BEILSTEIN REFERENCE NO. :: 0172873

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H14-N2-O

MOLECULAR WEIGHT :: 202.28

WISWESSER LINE NOTATION :: T B656 EM HMT&&J LO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 415 mg/kg/5W-C

TOXIC EFFECTS :: Endocrine - changes in pituitary weight Related to Chronic Data - changes in ovarian weight Related to Chronic Data - changes in uterine weight

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,47,1978

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 440 mg/kg/5W-I

TOXIC EFFECTS :: Vascular - regional or general arteriolar constriction Endocrine - changes in spleen weight Related to Chronic Data - changes in uterine weight

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,47,1978

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UV0725000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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