N-desmethylchlorpheniramine
Names
[ CAS No. ]:
20619-12-9
[ Name ]:
N-desmethylchlorpheniramine
[Synonym ]:
Anti-Nlrb1
UNII-0D64JQ680A
Mono-N-desmethyl chlorpheniramine
Chlorphenamine impurity C
Desmethylchlorpheniramine
Anti-Birc1
Desmcp
N-Desmethylchlorpheniramine
Chemical & Physical Properties
[ Density]:
1.118g/cm3
[ Boiling Point ]:
387.7ºC at 760mmHg
[ Molecular Formula ]:
C15H17ClN2
[ Molecular Weight ]:
260.76200
[ Flash Point ]:
188.3ºC
[ Exact Mass ]:
260.10800
[ PSA ]:
24.92000
[ LogP ]:
3.86730
[ Vapour Pressure ]:
3.22E-06mmHg at 25°C
[ Index of Refraction ]:
1.566
Safety Information
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Chromatogr. B. Biomed. Sci. Appl. 707(1-2) , 235-40, (1998)
The enantiomers of chlorpheniramine and its monodesmethyl metabolite were determined separately in urine by using a coupled achiral-chiral chromatographic system. The two enantiomers of the studied co...
Urinary excretion of chlorpheniramine and its metabolites in children.J. Pharm. Sci. 73(5) , 595-9, (1984)
The pharmacokinetics and urinary excretion of chlorpheniramine were studied in 11 patients, aged 6-16 years, with allergic rhinitis. In these children, chlorpheniramine had a mean elimination half-lif...
Skin permeation of chlorpheniramine maleate and detection of demethylated metabolites by high-performance liquid chromatography.J. Pharm. Sci. 77(2) , 188-90, (1988)