10H-Phenothiazin-3-ol,8-chloro-10-[3-(dimethylamino)propyl]-
Names
[ CAS No. ]:
2095-62-7
[ Name ]:
10H-Phenothiazin-3-ol,8-chloro-10-[3-(dimethylamino)propyl]-
[Synonym ]:
7-OCPZ
7-OHCPZ
7-Hydroxychlorpromazine
7-hydroxychlorpropazine
Chemical & Physical Properties
[ Density]:
1.281g/cm3
[ Boiling Point ]:
513.6ºC at 760 mmHg
[ Molecular Formula ]:
C17H19ClN2OS
[ Molecular Weight ]:
334.86400
[ Flash Point ]:
264.4ºC
[ Exact Mass ]:
334.09100
[ PSA ]:
52.01000
[ LogP ]:
4.66500
[ Vapour Pressure ]:
3.59E-11mmHg at 25°C
[ Index of Refraction ]:
1.644
[ Storage condition ]:
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SO0175000
- CHEMICAL NAME :
- Phenothiazine, 2-chloro-10-(3-(dimethylamino)propyl)-7-hydroxy-
- CAS REGISTRY NUMBER :
- 2095-62-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H19-Cl-N2-O-S
- MOLECULAR WEIGHT :
- 334.89
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B3N1&1 EG LQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 119 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,715,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 4,2425,1965
Safety Information
[ HS Code ]:
2934300000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934300000
[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%