Carperone
Names
[ CAS No. ]:
20977-50-8
[ Name ]:
Carperone
[Synonym ]:
CARBAMIC ACID,ISOPROPYL-,1-(3-(p-FLUOROBENZOYL)PROPYL)PIPERID-4-YL ESTER
Carperona [INN-Spanish]
Carperonum
1-(3-(4-Fluorobenzoyl)propyl)-4-piperidyl N-isopropylcarbamate
Carperonum [INN-Latin]
AL-1021
Carperone
(1-Methylethyl)carbamic acid,1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl ester
1-(4-fluoro-phenyl)-4-(4-isopropylcarbamoyloxy-piperidin-1-yl)-butan-1-one
Carperona
Chemical & Physical Properties
[ Density]:
1.15g/cm3
[ Boiling Point ]:
493.7ºC at 760mmHg
[ Molecular Formula ]:
C19H27FN2O3
[ Molecular Weight ]:
350.42800
[ Flash Point ]:
252.4ºC
[ Exact Mass ]:
350.20100
[ PSA ]:
62.13000
[ LogP ]:
3.52990
[ Vapour Pressure ]:
6.85E-10mmHg at 25°C
[ Index of Refraction ]:
1.533
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FB3235000
- CHEMICAL NAME :
- Carbamic acid, isopropyl-, 1-(3-(p-fluorobenzoyl)propyl)piperid-4-yl ester
- CAS REGISTRY NUMBER :
- 20977-50-8
- BEILSTEIN REFERENCE NO. :
- 1551021
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C19-H27-F-N2-O3
- MOLECULAR WEIGHT :
- 350.48
- WISWESSER LINE NOTATION :
- T6NTJ A3VR DF& DOVMY1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 2140 ug/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy) Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 11,779,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 310 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 265 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 44 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
Safety Information
[ HS Code ]:
2933399090
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%