RAD51-IN-17
Names
[ CAS No. ]:
2101739-18-6
[ Name ]:
RAD51-IN-17
Biological Activity
[Description]:
RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines; also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation; a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers.
[References]
References 1. Ward A, et al. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3096-3100. View Related Products by Target DNA Repair Protein
Chemical & Physical Properties
[ Molecular Formula ]:
C22H16ClN3O
[ Molecular Weight ]:
373.84
[ Storage condition ]:
-20°C