EML-405

Names

[ CAS No. ]:
2101954-79-2

[ Name ]:
EML-405

Biological Activity

[Description]:

EML-405 (EML405) is a small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 14 uM; shows novel interaction with the Tudor-domain-containing protein Spindlin1 (SPIN1).

[References]

References 1. Bae N, et al. Nat Chem Biol. 2017 May 15. doi: 10.1038/nchembio.2377. 2. Wang W, et al. EMBO Rep. 2011 Oct 28;12(11):1160-6. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₆H₅₁N₅O₂

[ Molecular Weight ]:
585.837

Related Compounds

EML-631
EML 425
EML-633
CTCB-405
Chromate(2-), [2,4-dihydro-4-[(2-hydroxy-4-nitrophenyl)azo]-5-methyl-2-phenyl-3H-pyrazol-3-onato(2-)][4-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-3-hydroxy-1-naphthalenesulfonato(3-)]-, disodium
SAR-405
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
I+/--Methyldibenzo[b,e][1,4]dioxin-2-methanol
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide