3-Chloro-2-fluoroaniline
Names
[ CAS No. ]:
2106-04-9
[ Name ]:
3-Chloro-2-fluoroaniline
[Synonym ]:
3-Chloro-2-fluorobenzenamine
3-chloro-fluoroaniline
MFCD00069415
Benzenamine, 3-chloro-2-fluoro-
3-chloro-2-fluorophenylamine
2-fluoro-3-chloraniline
3-chloro-2-fluoraniline
3-Chloro-2-fluoroaniline
ZR CG BF
EINECS 218-283-6
3-chloro-2-fluoro-aniline
2-fluoro-3-chloroaniline
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
218.6±20.0 °C at 760 mmHg
[ Molecular Formula ]:
C6H5ClFN
[ Molecular Weight ]:
145.562
[ Flash Point ]:
86.0±21.8 °C
[ Exact Mass ]:
145.009460
[ PSA ]:
26.02000
[ LogP ]:
2.26
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.570
MSDS
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H315-H318-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26-S36-S36/37/39-S39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2921420090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Bioorg. Med. Chem. Lett. 24(18) , 4455-9, (2014)
The reference standard AZD8931{2-(4-((4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)-N-methylacetamide} (11a) was synthesized from methyl 4,5-dimethoxy-2-nitrobenzoate...
Yaws CL.Thermophysical Properties of Chemicals and Hydrocarbons 2nd ed.,, (2014), 522
Synthesis of 2-Chloro-3-fluorobromobenzene [J]. Zhao HY and Pan YQ
Chem. World 11 , 010, (2011)