Methyl acetobromo-α-D-glucuronate

Names

[ Name ]:
Methyl acetobromo-α-D-glucuronate

[Synonym ]:
Acetobromo-α-D-glucuronic acid, methyl ester
Methyl 2,3,4-tri-O-acetyl-α-D-glucopyranosyluronate bromide
Methyl acetobromo-α-D-glucuronate
Acetobromo-α-D-glucuronic acid methyl ester
EINECS 244-203-4
(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
Acetobromo-alpha-D-glucuronic acid methyl ester
α-D-Glucopyranuronic acid, 1-bromo-1-deoxy-, methyl ester, triacetate
α-D-Glucopyranuronosyl bromide, methyl ester, triacetate
MFCD00061613

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
388.6±42.0 °C at 760 mmHg

[ Melting Point ]:
80-110 °C(lit.)

[ Molecular Formula ]:
C₁₃H₁₇BrO₉

[ Molecular Weight ]:
397.173

[ Flash Point ]:
188.8±27.9 °C

[ Exact Mass ]:
396.005585

[ PSA ]:
114.43000

[ LogP ]:
2.20

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.505

[ Storage condition ]:
−20°C

[ Stability ]:
Moisture and Temperature Sensitive

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Mitochondrial KATP channel inhibition blunts arrhythmia protection in ischemic exercised hearts.

Am. J. Physiol. Heart Circ. Physiol. 299 , H175-183, (2010)

The mechanisms responsible for anti-arrhythmic protection during ischemia-reperfusion (IR) in exercised hearts are not fully understood. The purpose of this investigation was to examine whether the AT...

Glucuronidation of HMR1098 in human microsomes: evidence for the involvement of UGT1A1 in the formation of S-glucuronides.

Drug Metab. Dispos. 31 , 1027-1034, (2003)

HMR1098, a novel KATP-blocking agent, is metabolized to form an S-glucuronide in rat and dog bile. Synthesis of the S-glucuronide metabolite was studied in human liver and kidney microsomes. Recombina...

Single channel studies of the ATP-regulated potassium channel in brain mitochondria.

J. Bioenerg. Biomembr. 41 , 323-334, (2009)

Mitochondrial potassium channels in the brain have been suggested to have an important role in neuroprotection. The single channel activity of mitochondrial potassium channels was measured after recon...