Dasatinib carbaldehyde

Names

[ CAS No. ]:
2112837-79-1

[ Name ]:
Dasatinib carbaldehyde

Biological Activity

[Description]:

PROTAC ABL binding moiety 4, the Dasatinib (ABL inhibitor) moiety, binds to IAP ligand via a linker to form SNIPER [1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22ClN7O2S

[ Molecular Weight ]:
471.96

[ Storage condition ]:
2-8°C