Amidinothiourea
Names
[ CAS No. ]:
2114-02-5
[ Name ]:
Amidinothiourea
[Synonym ]:
Guthimin
MFCD00014472
2-imino-4-thiobiuret
Amidinothiourea
EINECS 218-308-0
1-Carbamimidoylthiourea
Thiourea, (aminoiminomethyl)-
Gutimine
N-Amidinothiourea
1-[Amino(imino)methyl]thiourea
Guthimine
Thiodicyanodiamidine
Thiourea,(aminoiminomethyl)
Thiourea, N-(aminoiminomethyl)-
1-Amidinothiourea
Guanylthiourea
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
231.2±23.0 °C at 760 mmHg
[ Melting Point ]:
171-173 °C(lit.)
[ Molecular Formula ]:
C2H6N4S
[ Molecular Weight ]:
118.161
[ Flash Point ]:
93.7±22.6 °C
[ Exact Mass ]:
118.031319
[ PSA ]:
120.01000
[ LogP ]:
-1.77
[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.756
[ Water Solubility ]:
7 g/100 mL (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YR8250000
- CHEMICAL NAME :
- Urea, 1-amidino-2-thio-
- CAS REGISTRY NUMBER :
- 2114-02-5
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C2-H6-N4-S
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,46,1953
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
S26-S37/39-S24/25-S23
[ RIDADR ]:
2811
[ WGK Germany ]:
3
[ RTECS ]:
YR8250000
[ Packaging Group ]:
III
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Nerv. Sist. 27 , 8-16, (1988)
[The action of amtizol and gutimin on the respiratory metabolism of the neuron].
Farmakol. Toksikol. 54(3) , 22-4, (1991)
The effects of antihypoxants gutimine and amtisole on oxygen consumption by the intact nerve cell of the invertebrate and the activity of NADN-DH and SDH-dependent ways of oxidation in the cell were s...
[Ultrastructural features of heart insufficiency and its correction during the post-asphyxia period].Biull. Eksp. Biol. Med. 109(1) , 72-4, (1990)
The ultrastructure of myocardium was studied in the experiments on rats during 24 hours after 6-min mechanical asphyxia with following clinical death. It has been established that the contractile card...