NHWD-870
Names
[ CAS No. ]:
2115742-03-3
[ Name ]:
NHWD-870
Biological Activity
[Description]:
NHWD-870 is a potent, orally active and selective BET family bromodomain and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2.7 nM), and BRDT. NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction. NHWD-870 increases tumor apoptosis and inhibits tumor proliferation.
Chemical & Physical Properties
[ Molecular Formula ]:
C29H29N7O
[ Molecular Weight ]:
491.59