O-Desmethylangolensin

Names

[ Name ]:
O-Desmethylangolensin

[Synonym ]:
O-Desmethylangolensin
o-demethylangolensin
O-Demethylangolesin

Biological Activity

[Description]:

O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity[1][2].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[In Vitro]

O-Desmethylangolensin (O-DMA) inhibits the growth of HepG2 cells at higher doses (~30% decrease at 75 μM)[2].

[References]

[1]. Elizabeth J Reverri, et al. Metabolomics reveals differences between three daidzein metabolizing phenotypes in adults with cardiometabolic risk factors. Mol Nutr Food Res. 2017 Jan;61(1).

[2]. Eun Jeong Choi, et al. The antioxidant activity of daidzein metabolites, O‑desmethylangolensin and equol, in HepG2 cells. Mol Med Rep. 2014 Jan;9(1):328-32.

Chemical & Physical Properties

[ Density]:
1.329g/cm3

[ Boiling Point ]:
483.3ºC at 760mmHg

[ Molecular Formula ]:
C₁₅H₁₄O₄

[ Molecular Weight ]:
258.26900

[ Flash Point ]:
260.2ºC

[ Exact Mass ]:
258.08900

[ PSA ]:
77.76000

[ LogP ]:
2.78980

[ Vapour Pressure ]:
5.76E-10mmHg at 25°C

[ Index of Refraction ]:
1.652

[ Storage condition ]:
2-8°C

Safety Information

[ HS Code ]:
2914501900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%