YW1159
Names
[ CAS No. ]:
2131223-69-1
[ Name ]:
YW1159
[Synonym ]:
1-(2-Fluorophenyl)-5-methyl-N-(2-quinolinyl)-1H-1,2,3-triazole-4-carboxamide
1H-1,2,3-Triazole-4-carboxamide, 1-(2-fluorophenyl)-5-methyl-N-2-quinolinyl-
Biological Activity
[Description]:
YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.
[In Vitro]
YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.It is not cytotoxic to HEK293 cells following incubations of up to 24 hours but cell viability is decreased in a concentration-dependent manner after 72 hours.
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Molecular Formula ]:
C19H14FN5O
[ Molecular Weight ]:
347.346
[ Exact Mass ]:
347.118225
[ LogP ]:
2.72
[ Index of Refraction ]:
1.688