L-Alanine (2-D)

Names

[ Name ]:
L-Alanine (2-D)

[Synonym ]:
Alanine-2-d
DL-Alanine-2-d
MFCD00084105
L-alanine-2-d1
L-Alanine-2-d
(2-H)Alanine
L-Methionine-methyl-13C,N-t-Boc derivative
L-alanine-C*-d1

Biological Activity

[Description]:

L-Alanine-2-d1 is the deuterium labeled L-Alanine-2[1].

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
212.9±23.0 °C at 760 mmHg

[ Melting Point ]:
47-50ºC(lit.)

[ Molecular Formula ]:
C₃H₆DNO₂

[ Molecular Weight ]:
90.10

[ Flash Point ]:
82.6±22.6 °C

[ Exact Mass ]:
90.053955

[ PSA ]:
63.32000

[ LogP ]:
-0.68

[ Vapour Pressure ]:
0.1±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.460

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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