KEA1-97

Names

[ Name ]:
KEA1-97

Biological Activity

[Description]:

KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3; activates caspases, and induces apoptosis without affecting thioredoxin activity, impairs triple-negative breast cancer cell survival; impairs in vivo breast tumor xenograft growth.

[References]

References 1. Anderson KE, et al. ACS Chem Biol. 2017 Oct 20;12(10):2522-2528. View Related Products by Target Caspase

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₉Cl₂FN₄

[ Molecular Weight ]:
335.163

Related Compounds

DH 97
FLUOROIODOACETONITRILE 97
DH 97
ruthenium-97
331457-97-7
technetium-97
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
4-(3-Isopropyl-1-methyl-1h-1,2,4-triazol-5-yl)piperidine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
2-Amino-4-bromonicotinic acid