ALPHA-D-GLUCOSAMINE 1-PHOSPHATE

Names

[ Name ]:
ALPHA-D-GLUCOSAMINE 1-PHOSPHATE

[Synonym ]:
GP1
Glucosamine 1-phosphate
alpha-D-glucosamine 1-phosphate
[(2R,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] dihydrogen phosphate
2-amino-2-deoxy-1-o-phosphono-|A-d-glucopyranose
D-glucosamine 1-phosphate

Biological Activity

[Description]:

α-D-Glucosamine 1-phosphate is an E.coli metabolite. α-D-Glucosamine 1-phosphate is one of the precursors of peptidoglycan synthesis[1][2].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Mengin-Lecreulx D, et al. Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli. J Biol Chem. 1996 Jan 5;271(1):32-9.

[2]. Craggs PD, et al. The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU. Biochemistry. 2018 Jun 19;57(24):3387-3401.

Chemical & Physical Properties

[ Density]:
1.81g/cm3

[ Boiling Point ]:
596ºC at 760mmHg

[ Molecular Formula ]:
C₆H₁₄NO₈P

[ Molecular Weight ]:
259.15

[ Flash Point ]:
314.3ºC

[ Exact Mass ]:
259.04600

[ PSA ]:
172.51000

[ Vapour Pressure ]:
1.09E-16mmHg at 25°C

[ Index of Refraction ]:
1.605

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Articles

Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli.

J. Biol. Chem. 271(1) , 32-9, (1996)

Two different approaches to identify the gene encoding the phosphoglucosamine mutase in Escherichia coli were used: (i) the purification to near homogeneity of this enzyme from a wild type strain and ...

A new family of glucose-1-phosphate/glucosamine-1-phosphate nucleotidylyltransferase in the biosynthetic pathways for antibiotics.

J. Am. Chem. Soc. 127(6) , 1711-8, (2005)

Aminoglycoside antibiotics are composed of aminosugars and a unique aminocyclitol aglycon including 2-deoxystreptamine (DOS), streptidine, actinamine, etc., and nucleotidylyltransferases, sugar modify...

[An unusual lipid A from a marine bacterium Chryseobacterium scophtalmum CIP 104199T].

Bioorg. Khim. 32(5) , 538-45, (2006)

The hydrolysis of defatted cells of the marine bacterium Chryseobacterium scophtalmum CIP 104199T with 10% acetic acid (3 h, 100 degrees C) led to an unusual lipid A (LA) (yield 0.6%), obtained for th...