Benzoic acid,4-(3,3-dimethyl-1-triazen-1-yl)-, ethyl ester
Names
[ CAS No. ]:
21600-51-1
[ Name ]:
Benzoic acid,4-(3,3-dimethyl-1-triazen-1-yl)-, ethyl ester
[Synonym ]:
at 2052
Chemical & Physical Properties
[ Density]:
1.09g/cm3
[ Boiling Point ]:
313ºC at 760mmHg
[ Molecular Formula ]:
C11H15N3O2
[ Molecular Weight ]:
221.25600
[ Flash Point ]:
143.1ºC
[ Exact Mass ]:
221.11600
[ PSA ]:
54.26000
[ LogP ]:
2.42360
[ Vapour Pressure ]:
0.00051mmHg at 25°C
[ Index of Refraction ]:
1.528
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG9125000
- CHEMICAL NAME :
- Benzoic acid, p-(3-dimethyltriazeno)-, ethyl ester
- CAS REGISTRY NUMBER :
- 21600-51-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C11-H15-N3-O2
- MOLECULAR WEIGHT :
- 221.29
- WISWESSER LINE NOTATION :
- 2OVR DNUNN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Blood - leukopenia Blood - thrombocytopenia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 760 mg/kg/19W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 805 mg/kg/23W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Blood - lymphoma, including Hodgkin's disease
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 760 mg/kg/19W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TYPE OF TEST :
- Host-mediated assay
- TEST SYSTEM :
- Rodent - mouse Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 8852 mg/kg
- REFERENCE :
- CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 9,365,1974
Safety Information
[ HS Code ]:
2916399090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%