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MCL-1/BCL-2-IN-3

Names

[ CAS No. ]:
2163793-55-1

[ Name ]:
MCL-1/BCL-2-IN-3

Biological Activity

[Description]:

MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H25BrN2O5S

[ Molecular Weight ]:
569.47

Related Compounds