5-nitropyrimidine-4,6-diol

Names

[ Name ]:
5-nitropyrimidine-4,6-diol

[Synonym ]:
4,6-Pyrimidinediol, 5-nitro-
6-Hydroxy-5-nitro-4(1H)-pyrimidinone
5-Nitro-4,6-pyrimidinediol
EINECS 218-504-6
5-nitropyrimidine-4,6-diol
5-nitro-1H-pyrimidine-4,6-dione
MFCD00006110
5-Nitro-4,6-dihydroxypyrimidine
4,6-Dihydroxy-5-nitropyriMidine
4,6-Dihydroxy-5-nitropyrimdine
4,6-Dihydroxy-5-nitroprimidine

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
303.5±37.0 °C at 760 mmHg

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
C₄H₃N₃O₄

[ Molecular Weight ]:
157.084

[ Flash Point ]:
137.4±26.5 °C

[ Exact Mass ]:
157.012360

[ PSA ]:
112.06000

[ LogP ]:
-0.73

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.701

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Phenobarbital induction and chemical synergism demonstrate the role of UDP-glucuronosyltransferases in detoxification of naphthalophos by Haemonchus contortus larvae.

Antimicrob. Agents Chemother. 58(12) , 7475-83, (2014)

We used an enzyme induction approach to study the role of detoxification enzymes in the interaction of the anthelmintic compound naphthalophos with Haemonchus contortus larvae. Larvae were treated wit...

Inhibition of UDP-glucuronyltransferase activity in rat liver microsomes by pyrimidine derivatives.

Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. 112(3) , 321-5, (1995)

Thirty-one differently substituted pyrimidine bases were tested for their inhibitory effect on the glucuronidation of 4-nitrophenol and phenolphthalein by rat liver microsomes. 5-Nitrouracil (compound...

The activity of thymidine phosphorylase obtained from human uterine leiomyomas and studied in the presence of pyrimidine derivatives.

Z. Naturforsch., C, J. Biosci. 52(9-10) , 670-5, (1997)

Partially purified samples of thymidine phosphorylase were obtained from four preparations of human uterine leiomyomas and uteri using the method of Yoshimura et al. (1990), Biochim. Biophys. Acta 103...