(Rac)-IDO1-IN-5

Names

[ Name ]:
(Rac)-IDO1-IN-5

Biological Activity

[Description]:

(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₅FN₂O₃

[ Molecular Weight ]:
396.45

Related Compounds

(S)-IDO1-IN-5
(Rac)-5-Hydroxymethyl Tolterodine
(rac)-(5-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethoxy}-indol-1-yl)-acetic acid
rac 5-Desfluoro Voriconazole
rac-5-isopropyl-2-oxo-cyclohexanecarbaldehyde
rac 5-Carboxy Desisopropyl Tolterodine
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
3-(pentafluoroethyl)-1-(propan-2-yl)-4-(trifluoromethyl)-1H-pyrazol-5-amine
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4-Amino-3-[2-(propan-2-yl)-1,3-thiazol-5-yl]butanoic acid
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine