4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
Names
[ CAS No. ]:
21928-50-7
[ Name ]:
4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
[Synonym ]:
4-hydroxy-4-[(4-chloro-3-trifluoromethyl)phenyl]piperidine
Piperidine alcohol
4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidine
4-(p-chloro-m-trifluoromethylphenyl)-4-hydroxypiperidine
4-(4-chloro-3-trifluoromethylphenyl)-4-hydroxypiperidine
4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
4-[4-chlor-3-(trifluormethyl)phenyl]piperidin-4-ol
4-(4-Chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol
4-(4-Chloro-3-(trifluoromethyl)phenyl)-4-piperidinol
4-(3-trifluoromethyl-4-chlorophenyl)-4-hydroxy piperidine
EINECS 244-665-7
MFCD00066999
Chemical & Physical Properties
[ Density]:
1.347 g/cm3
[ Boiling Point ]:
333.3ºC at 760 mmHg
[ Melting Point ]:
138-141 °C(lit.)
[ Molecular Formula ]:
C12H13ClF3NO
[ Molecular Weight ]:
279.68600
[ Flash Point ]:
155.4ºC
[ Exact Mass ]:
279.06400
[ PSA ]:
32.26000
[ LogP ]:
3.25860
[ Vapour Pressure ]:
5.48E-05mmHg at 25°C
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S22-S24/25-S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Bioorg. Med. Chem. 17 , 3588-3594, (2009)
Direct anti-tuberculosis screening of commercially available compound libraries identified a novel piperidinol with interesting anti-tuberculosis activity and drug like characteristics. To generate a ...
Rhodium catalyzed hydroformylation of 1, 1-bis (p-fluorophenyl) allyl or propargyl alcohol: a key step in the synthesis of Fluspirilen and Penfluridol. Botteghi C, et al.Tetrahedron 57(8) , 1631-1637, (2001)