AS602868

Names

[ CAS No. ]:
219773-55-4

[ Name ]:
AS602868

[Synonym ]:
a4715
spc-839

[Description]:

SPC 839 (compound 10) is an orally active inhibitor of AP-1 and NF-kB mediated transcriptional activation with IC50 of 0.008 μM[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[In Vivo]

SPC 839 (compound 10) (30 mg/kg, p.o., 21 days) 在佐剂诱导的关节炎大鼠模型中显示显著活性，使未注射足部肿胀减少 65%[1]。

[References]

[ Density]:
1.475

[ Molecular Formula ]:
C₁₈H₁₄N₄O₃S

[ Molecular Weight ]:
366.39

[ Exact Mass ]:
366.07900

[ PSA ]:
115.89000

[ LogP ]:
2.36870