molinate
Names
[ CAS No. ]:
2212-67-1
[ Name ]:
molinate
[Synonym ]:
UNII:68N5G08DJQ
Molmate
Jalan
EINECS 218-661-0
S-ethyl hexahydro-1H-azepine-1-carbothioate
Sakkimol
S-Ethyl 1-azepanecarbothioate
S-Ethyl azepane-1-carbothioate
S-ethyl perhydroazepine-1-carbothioate
S-ethylhexahydro-1H-azepine-1-carbothioate
S-ethyl perhydroazepine-1-thiocarboxylate
Molinex
S-ethyl-N,N-hexamethylene-thiocarbamate
Higalnate
Felan
MFCD00055352
molinate
Stauffer R 4572
Ordram
1H-Azepine-1-carbothioic acid, hexahydro-, S-ethyl ester
S-Ethylazepan-1-carbothioat
Hydram
ethyl 1-hexamethyleneiminecarbothiolate
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
279.0±23.0 °C at 760 mmHg
[ Molecular Formula ]:
C9H17NOS
[ Molecular Weight ]:
187.302
[ Flash Point ]:
122.6±22.6 °C
[ Exact Mass ]:
187.103088
[ PSA ]:
45.61000
[ LogP ]:
3.21
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.512
[ Water Solubility ]:
0.08 g/100 mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CM2625000
- CHEMICAL NAME :
- 1H-Azepine-1-carbothioic acid, hexahydro-, S-ethyl ester
- CAS REGISTRY NUMBER :
- 2212-67-1
- BEILSTEIN REFERENCE NO. :
- 1239196
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 22
- MOLECULAR FORMULA :
- C9-H17-N-O-S
- MOLECULAR WEIGHT :
- 187.33
- WISWESSER LINE NOTATION :
- T7NTJ AVS2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 369 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2100 mg/m3/1H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1167 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 657 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 530 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Sense Organs and Special Senses (Eye) - changes in extra-ocular muscles Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 545 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- >200 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3536 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 720 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3952 mg/kg/43W-I
- TOXIC EFFECTS :
- Endocrine - other changes Blood - normocytic anemia Nutritional and Gross Metabolic - body temperature decrease
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7818 mg/kg/17W-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - body temperature decrease Related to Chronic Data - death
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 113 mg/m3/30D-I
- TOXIC EFFECTS :
- Liver - liver function tests impaired Kidney, Ureter, Bladder - other changes in urine composition Blood - other changes
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4500 ug/m3/17W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 4500 ug/m3/17W-I
- TOXIC EFFECTS :
- Liver - liver function tests impaired Blood - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 324 mg/kg
- SEX/DURATION :
- male 90 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females) Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1620 mg/kg
- SEX/DURATION :
- male 90 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- DOSE :
- 640 ug/m3/6H
- SEX/DURATION :
- male 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- DOSE :
- 600 ug/m3/6H
- SEX/DURATION :
- male 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 242,279,1990 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
Safety Information
[ Symbol ]:
GHS07, GHS08, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H332-H317-H351-H361-H373-H410
[ Precautionary Statements ]:
P201-P261-P273-P280-P304 + P340 + P312-P308 + P313
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T,N,Xn
[ Risk Phrases ]:
R20/22
[ Safety Phrases ]:
S36/37-S46-S60-S61
[ RIDADR ]:
2902
[ RTECS ]:
CM2625000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2933990017
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990017
[ Summary ]:
2933990017 6,7-dihydrodipyrido[1,2-a:2',1'-c]pyrazine-5,8-diium bromide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%
Articles
Anal. Chem. 86(11) , 5541-6, (2014)
Small compounds cannot bind simultaneously to two antibodies, and thus, their immunodetection is limited to competitive formats in which the analyte is indirectly quantitated by measuring the unoccupi...
Field dissipation and environmental hazard assessment of clomazone, molinate, and thiobencarb in Australian rice culture.J. Agric. Food Chem. 54(19) , 7213-20, (2006)
The fates of clomazone [2-(2-chlorophenyl)methyl-4,4-dimethyl-3-isoxazolidinone], molinate (S-ethyl hexahydro-1-H-azepine-1-carbothioate), and thiobencarb {S-[(4-chlorophenyl)methyl]diethylcarbamothio...
Photocatalytic degradation of molinate in aqueous solutions.Environ. Sci. Pollut. Res. Int. 21(21) , 12294-304, (2014)
In this study, the degradation of molinate through heterogeneous photocatalysis, using two different types of the semiconductor TiO2 as photocatalyst, as well as through homogeneous treatment, applyin...